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病理报告
<左乳结节>结合HE形态及肿瘤细胞免疫表型:Ckpan(AE1/AE3)、ER(浸(+)润性癌与原位癌均:强+,95%)、PR(浸润性癌与原位癌均:中-弱+,70%)、CerbB-2-Roche(2+)、CK5/6(-)、P63(-)、Ki67(+,约10%)、GATA-3(+)、E-C(+)、AR(弱+,约40%)SOX-10(-) TROP2(3+)
穿刺组织:浸润性癌,考虑为非特殊类型浸润性癌(WHOI级;5分:腺管形成2分、核多形性2分、核分裂像1分),建议进一步结合临床考虑,必要时术后大标本进一步明确类型及分级;周围可见中等核级导管内癌。
Pathological Report
<Left Breast Nodule> Based on the HE morphology and tumor cell immunophenotype: Ckpan (AE1/AE3), ER (for both invasive cancer and in situ cancer: strong+, 95%), PR (for both invasive cancer and in situ cancer: moderate to weak+, 70%) CerbB-2-Roche (2+), CK5/6, P63 (-), Ki67 (+, approximately 10%), AR (weak+, approximately GATA-3 (+), E-C40%), TROP2 (3+), SOX-10 (-). Biopsy tissue: Invasive cancer, considered as a non-specific type of invasive cancer (WHO grade I: 5 points: glandular duct formation 2 points, nuclear pleomorphism 2 points, mitotic figures 1 point), it is recommended to further consider in combination with clinical factors, and if necessary, a large specimen after surgery is recommended to further clarify the type and grade; Surrounding areas show moderately nuclear grade intraductal carcinomas.